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The BIOFIRE System and Your Immune System The BIOFIRE System provides syndromic infectious disease testing, which allows healthcare providers to select the most appropriate test, the first time. Patients benefit from faster diagnosis and more targeted treatments. Clinicians benefit from improved antibiotic stewardship. Labs are more efficient and can make cost savings. The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes. The panel provides semiquantitative results that take less than an hour. Respiratory The burning of biomass (wood plants, agro-forestry and other organic material) produces gaseous pollutants as well as fine particles of matter that adversely affect the respiratory system. Furthermore, the environmental issues caused by forest fires, such as droughts, can be exacerbated by climate change, which can increase their negative impacts on human health. In the United States, wildfire smoke has been linked to hospitalizations for respiratory diseases, such as asthma, COPD and lung cancer. Furthermore, this type of air pollution can be an underlying risk factor for cardiovascular disease and a significant contributing factor to the burden of disease among the most vulnerable populations which includes those who are of lower socioeconomic status (SES). In the COVID-19 pandemic, many communities were exposed levels of air pollution resulting from wildfires. However the public health response to this environmental issue has been sporadic and mostly focused on communication regarding symptom management. This knowledge gap is alarming considering the evidence that smoking cigarettes and other causes of air pollution can lead to health problems. Researchers are now looking at the best way to safeguard public's health in the event of future events of this kind. NIH is funding research on this critical public health problem through the BLUE CORAL study as well as its successor FIRE CORAL. For the first time an prospective cohort study will evaluate long-term effects of exposure to smoke from wildfires as well as other sources. FIRE CORAL enrolls adults who are hospitalized for COVID-19 index episodes and speak English or Spanish, but are not pregnant. The protocol for Fire Coral includes a battery in-person assessments that objectively measure the pulmonary function testing, lung imaging and functional assessment. Smoke and other particles can trigger or worsen respiratory conditions such as emphysema, COPD, and pneumonia. Smoke exposure can cause adverse effects on health. To lessen or stop these effects, you should avoid outdoor activities and use the EPA “N95” mask. The mask is designed to trap fine particles. Smoking can cause irritation to the eyes, throat and nose. To reduce the symptoms, drink plenty of water and take medications that reduce inflammation, such corticosteroids. Bloodstream The bloodstream is your first line of defense against germs that invade your system. Dendritic cells, which are special cells, are akin to your fire department's call center; they gather antigens (molecules that trigger an immune response) from invaders and release proteins that trigger other white blood cells to come fight them. The total white blood cells, differentials and band cells increased following firefighters' firefighting activities as compared to levels following intense exercise without firefighting. Skin Dermatologists were concerned about the smoke and ash from the California wildfires could have an adverse effect on the skin of those exposed to these substances. Maria Wei is a graduate student at the University of California, Irvine. She examines how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22nd. The study by Wei shows that temperature of the skin fluctuates according to the length of time the body has been exposed. It can take as long as two hours for the skin of a person to reach its “flash point”—the moment at which it begins to burn and then turn to ash. It's crucial not to be near a campfire or fire, and you should always wear protective clothing when out during a hot or humid day. Forest fires will continue occur, despite the measures taken to stop wildfire pollution. Wei predicts that as the climate changes cause forests to burn more, the number of people suffering from wildfires will increase. This means that more people will have to wear hats, long sleeves, and thick moisturizers. Air pollution from wildfires can increase the severity of atopic skin dermatitis which causes itchy skin in a lot of people. She claims that the particles in smoke can clog up pores, making atopic skin worse. Another issue is the fact that atopic dermatitis tends to make people more sensitive to UV light, which can also be aggravated by wildfire smoke. This can result in people seeking out tanning salons and apply a tan with less protection. A treatment with ice and fire may help reduce atopic skin dermatitis symptoms however, it isn't recommended for those with an open wound or rash. Patients who suffer from acne are advised to avoid it, and if you're nursing or pregnant, it's recommended to avoid this treatment altogether. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' top membership MedSpa It's a highly effective result-driven facial that bridges the gap between a light facial and a peel without requiring any downtime. bio ethanol fire 's designed to smooth the skin, improve the appearance of rosacea, reduce acne scarring, diminish fine lines, and encourage the renewal of cells. It's an amazing treatment to give yourself a radiant glow. Infections The human body is comprised of a complex set of organs and tissue which work together to guard against infections. Infections can be caused by microorganisms such as parasites, viruses and bacteria which infect healthy cells and cause them to multiply in uncontrolled ways. Your immune system can react by displaying signs of illness. These symptoms could be anything from a snoring nose to a stomach that is upset as well as a fever, swollen lymph glands or an rash. The symptoms you experience can be affected by the type of infection, its location, and even your temperature. Infections can be spread through a variety of methods, but the most common are spread from person to by droppings that hang in the air after sneezing or coughing. Bacterial diseases like tuberculosis, strep throat, meningococcal disease, and Legionnaires' disease are spread through this method, along with some viral infections, such as the common cold and influenza. Some bacteria-related infections, like skin infections and sexually transmitted infections (STIs) such as gonorrhea and chlamydia, are spread by direct contact with infected tissues or mucous membranes, or through indirect contact with surfaces that are contaminated. Some bacterial infections are spread by insects like fleas, ticks, or mosquitoes. Viruses and some parasites are small enough to enter your bloodstream and infect your cells, which can lead to serious diseases like the common cold and AIDS. Fungi can cause a variety of skin ailments, like ringworm and athlete's foot, while some are a threat to the lungs and nervous system, such as the rabies virus. The BioFire PN Panel uses our innovative FilmArray technology to analyze a comprehensive list of pathogens that are involved in upper respiratory infections in sputum or the bronchoalveolar lavage samples. The kit includes a reagent bag that includes all the chemistry required to perform reverse transcription as well as nested multiplex PCR detection in one machine. This is a simple solution that helps clinicians identify and treat patients suffering from several respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.